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This method was first introduced in Chapter 3, but well review it here again. It is isolated from natural sources or produced by a synthetic process. Response Difference Diagnosis Pupil size to light greater in: Drug testing Defay anisocoria Tonic pupil (Adies) Horners syndrome Pharmacological Oculomotor palsy 12 mm difference Large Small Large Large Normal No change Absent Light Normal Dark Absent No change Absent No change None Pilocarpine (0.
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